How to live longer (and healthier) in 6 steps

With the accelerating pace of medical progress, for those of us still alive and healthy in 20 years, scientists say that incredible age-reversing treatments will be available. You may be able to add several decades of mobility, cognitive function, and independence according to these scientists. The question is, “Will you be around long enough to benefit from medical breakthroughs?” To increase your chances, here are 6 advanced strategies you can employ right now that can slow biological aging and improve overall health:

1. Cultivate a super healthy lifestyle:

  • Eat an organic, whole-food, plant-based diet and reduce portion sizes
  • Don’t smoke or drink
  • Drink plenty of water
  • Weight: Keep within 5% of optimal
  • Blood pressure: Keep under 120/80
  • Get sound sleep
  • Engage in strength-training exercise 3 days per week
  • Spend time outdoors
  • Manage your stress 

2. Maintain optimal bloodwork:

  • Cholesterol: 160-180 mg/dL
  • LDL: <100 mg/dL
  • HDL: >60 mg/dL
  • Triglycerides: <100 mg/dL
  • Cortisol (stress hormone): <13 ug/dL
  • Fibrinogen (blood clot potential): <276 mg/dL
  • hs-CRP (silent inflammation): <0.6 mg/L
  • Homocysteine (methylation): <7.1 μmol/L
  • Fasting glucose: 60-80 mg/dL
  • Fasting insulin: <6 uIU/mL
  • GlycoMark® (absence of post-mealtime glucose spiking): >19 mg/mL
  • Hemoglobin A1c (average glucose level for the last 90 days): <5.3%
  • Ferritin (iron): Women: 20-30 ng/mL; Men: 40-50 ng/mL
  • Vitamin D: 40-60 ng/mL

3. Boost AMPK activity and reduce excess mTOR signaling:

AMPK (adenosine monophosphate-activated protein kinase) is an enzyme that is involved in several longevity pathways and plays a key role in energy metabolism, insulin sensitivity, inflammation control, DNA repair, and muscle performance. Activating AMPK can reduce the risk of heart attack, stroke, hypertension, obesity, diabetes, osteoporosis, cancer, and Alzheimer’s disease. When mTOR (mechanistic target of rapamycin) is constantly elevated, it increases the risk of degenerative diseases.

4. Correct NAD+ deficits:

NAD+ (oxidized nicotinamide adenine dinucleotide) is a coenzyme crucial to cellular energy production. This coenzyme is found in every cell of the body and is necessary to make ATP (adenosine triphosphate) — the compound the body uses for fuel. Declining NAD+ levels are directly associated with aging. This leads to impaired mitochondrial function, resulting in numerous age-related diseases. Restoring NAD+ to more youthful levels can help rejuvenate an aging body and improve resistance to disease.

5. Remove senescent cells:

Cellular senescence is an age-related process in which old cells lose the ability to divide and create new cells. This process is one of the main causes of the physical signs of aging and manifests in various diseases, such as arthritis, osteoporosis, heart disease, cancer, diabetes, frailty, and dementia. Senescent cells accumulate over time and secrete pro-inflammatory and protein-degrading compounds that damage neighboring healthy cells and accelerate the aging process. Many scientists believe that by eradicating as many senescent cells as possible and suppressing the secretion of the harmful compounds of the remaining senescent cells, we could lead a more disease-free life, bring back a more youthful vigor, and extend lifespan.

6. Reset your genes: 

With aging, there is an increase in the expression of genes that promote inflammation, oxidative stress, insulin resistance, cancer, and tissue deterioration, along with a simultaneous decrease in the expression of genes that inhibit inflammation, oxidative stress, and cancer, and promote insulin sensitivity, DNA repair, and removal of damaged proteins. One of the most significant scientific discoveries in decades was the discovery of a blood protein that has recently been found to reset gene expression to a younger and healthier state. This opens the door to a whole new way to prevent and treat age-related diseases and restore a more youthful state of health.

Comments from Dr. Thomas: To circumvent degenerative disease and increase healthy life expectancy, I have been at the forefront by pioneering an innovative combination of diet, exercise, bioactive plant compounds, and repurposed medications to promote optimum bloodwork, boost AMPK activity and reduce excess mTOR signaling, correct NAD+ deficits, remove senescent cells, and reset genes, all to improve health, ward off illness, increase longevity, maximize brain function, and restore more youthful vigor. This is available exclusively to my concierge patients (click here).